Kaopectate   

   Return to Upjohn Memories Home Page  
 

Kaopectate was one of The Upjohn Company’s best-known products. It was for stopping diarrhea and it worked well. It was a very popular seller. For most of its product lifetime, the active ingredients were the clay kaolin and the thickener pectin. Prior to Kaopectate, medications for diarrhea had some risks. From 1902 to 1923, the “Improved” Upjohn medication contained opium for pain and chalk powder!

Kaopectate was introduced in 1913 and was still in the catalog eighty years later at the end of The Upjohn Company in 1995. Until 1984 it was only available as a suspension. Then tablets were introduced. Later on, caplets and chewable tablets were added. A Kaopectate concentrate, children’s liquid Kaopectate and children’s chewable tablets soon followed.

1990 Kaopectate TC Commercial on YouTube

The active ingredient in the 1990s changed from kaolin to attapulgite, which has a higher water absorption capacity.There was no evidence that pectin worked for diarrhea so that was removed. From 1962 to 1972 there was a combination Kaopectate and neomycin product.

Here are some Upjohn Kaopectate products I have in my bottle collection.




This 13-inch-high empty plastic bottle is a pharmacy display item from the 1970s and 80s.




    









In 2026, Kaopectate is still on the market, sold by Kramer Labs. Its active ingredient is now bismuth subsalicylate, which has much higher efficiency than attapulgite and kaolin clays.



   Return to Upjohn Memories Home Page